Upstream Bio, Inc. (UPB) Stock Total Returns

Growth of $10,000 chart

2024-10-11 to 2026-04-21
to
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Investment Performance

Final Value
$4,209
Total Return
-57.91%
CAGR
-43.30%
Dividends
$0.00
Yield on Cost
0.00%

Rolling Returns

1-Month (21 Trading Days)
Average+0.59%
Median+4.73%
Best+71.47%
Worst-76.32%
% of Windows Positive60.0%
1-Year (252 Trading Days)
Average+48.74%
Median+26.75%
Best+251.14%
Worst-18.42%
% of Windows Positive73.6%
3-Year (756 Trading Days)

Risk Metrics

Maximum Drawdown -77.84%
Average Drawdown -42.30%
Drawdown Duration 264 Trading Days
Sortino Ratio -0.10
Calmar Ratio -0.56
CVaR (5%) -15.39%

Yearly Returns

Year Percentage Abs. Return Dividends Taxes Trans. Costs
2026 partial -65.89% (-97.10% ann.) $6589.32 $0.00 $0.00 $0.00
2025 +65.15% +$6514.59 $0.00 $0.00 $0.00
2024 partial -25.27% (-73.12% ann.) $2527.27 $0.00 $0.00 $0.00

Market Regimes

about
Regime Period Percentage Annual Abs. Return Dividends Taxes Trans. Costs
Disinflationary easing / resilient growth / AI capex under oil-shock test partial October 11, 2024 – April 21, 2026 -57.91% -43.30% $5790.91 $0.00 $0.00 $0.00

Dividend History

Date Per Share Yield %
Total 0 payments
No dividends recorded.

All calculations use split-adjusted closing prices. Dividends are reinvested on the ex-dividend date at that day's closing price.

For each rolling window, returns are calculated at every possible starting point:

return = (value[i] ÷ value[i − windowSize] − 1) × 100

Windows
1-month = 21 trading days, 1-year = 252 trading days, 3-year = 756 trading days.
Statistics
Average: arithmetic mean. Median: middle value when sorted. Best / Worst: max and min. % Positive: share of windows with return > 0.

The series is segmented by calendar year:

return = (endValue ÷ startValue − 1) × 100

startValue is the last value of the prior year (or the first value for the initial year). Partial first/last years are flagged. Dividends, taxes, and transaction costs are scaled proportionally to the initial investment.

ORLY

CAGR 21.30% Total 58378.84% Final $5,847,884
1993-04-23 — 2026-04-21
ABUS

CAGR -1.86% Total -29.68% Final $7,032
2007-07-26 — 2026-04-21
FCBC

CAGR 6.66% Total 688.96% Final $78,896
1994-04-08 — 2026-04-21