Spyre Therapeutics, Inc. (SYRE) Stock Total Returns
Growth of $10,000 chart
2021-04-21 to 2026-04-21 to
$
%
%
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Investment Performance
Final Value
$3,664
Total Return
-63.36%
CAGR
-18.19%
Dividends
$0.00
Yield on Cost
0.00%
Rolling Returns
1-Month (21 Trading Days)
| Average | +5.49% |
| Median | -1.64% |
| Best | +459.41% |
| Worst | -74.68% |
| % of Windows Positive | 46.6% |
1-Year (252 Trading Days)
| Average | +48.39% |
| Median | -26.51% |
| Best | +1033.77% |
| Worst | -94.32% |
| % of Windows Positive | 42.9% |
3-Year (756 Trading Days)
| Average | +27.51% |
| Median | -66.83% |
| Best | +1800.55% |
| Worst | -87.99% |
| % of Windows Positive | 36.6% |
Risk Metrics
| Maximum Drawdown | -98.74% |
| Average Drawdown | -78.03% |
| Drawdown Duration | 1132 Trading Days (Unrecovered) |
| Sortino Ratio | 1.04 |
| Calmar Ratio | -0.18 |
| CVaR (5%) | -12.77% |
Yearly Returns
| Year | Percentage | Abs. Return | Dividends | Taxes | Trans. Costs |
|---|---|---|---|---|---|
| 2026 partial | +117.55% (+1190.51% ann.) | +$11755.15 | $0.00 | $0.00 | $0.00 |
| 2025 | +40.72% | +$4072.20 | $0.00 | $0.00 | $0.00 |
| 2024 | +8.18% | +$817.88 | $0.00 | $0.00 | $0.00 |
| 2023 | +91.29% | +$9128.94 | $0.00 | $0.00 | $0.00 |
| 2022 | -90.53% | $9052.64 | $0.00 | $0.00 | $0.00 |
| 2021 | -39.64% | $3964.42 | $0.00 | $0.00 | $0.00 |
| 2020 | +3.01% | +$301.04 | $0.00 | $0.00 | $0.00 |
| 2019 | +2.00% | +$200.27 | $0.00 | $0.00 | $0.00 |
| 2018 | +38.45% | +$3844.74 | $0.00 | $0.00 | $0.00 |
| 2017 | +24.37% | +$2436.77 | $0.00 | $0.00 | $0.00 |
| 2016 partial | -55.48% (-66.94% ann.) | $5547.59 | $0.00 | $0.00 | $0.00 |
Market Regimes
about| Regime | Period | Percentage | Annual | Abs. Return | Dividends | Taxes | Trans. Costs |
|---|---|---|---|---|---|---|---|
| Secular stagnation / QE / low inflation / duration bull partial | April 7, 2016 – February 19, 2020 | -15.86% | -4.37% | $1586.49 | $0.00 | $0.00 | $0.00 |
| Pandemic shock / liquidity crash | February 20, 2020 – March 23, 2020 | -48.33% | -99.95% | $4832.71 | $0.00 | $0.00 | $0.00 |
| Policy bazooka / monetary euphoria | March 24, 2020 – November 6, 2020 | +91.22% | +183.80% | +$9122.41 | $0.00 | $0.00 | $0.00 |
| Reopening reflation / fiscal boom / supply bottlenecks | November 9, 2020 – November 29, 2021 | -28.89% | -27.63% | $2888.89 | $0.00 | $0.00 | $0.00 |
| Inflation shock / duration crash / aggressive tightening | November 30, 2021 – November 9, 2022 | -79.17% | -81.09% | $7916.67 | $0.00 | $0.00 | $0.00 |
| Disinflation rebound / AI-led narrow bull / higher-for-longer | November 10, 2022 – September 17, 2024 | -25.95% | -14.96% | $2594.77 | $0.00 | $0.00 | $0.00 |
| Disinflationary easing / resilient growth / AI capex under oil-shock test partial | September 18, 2024 – April 21, 2026 | +146.10% | +76.32% | +$14609.80 | $0.00 | $0.00 | $0.00 |
Dividend History
| Date | Per Share | Yield % |
|---|---|---|
| Total | 0 payments |
No dividends recorded.
All calculations use split-adjusted closing prices. Dividends are reinvested on the ex-dividend date at that day's closing price.
For each rolling window, returns are calculated at every possible starting point:
return = (value[i] ÷ value[i − windowSize] − 1) × 100
- Windows
- 1-month = 21 trading days, 1-year = 252 trading days, 3-year = 756 trading days.
- Statistics
- Average: arithmetic mean. Median: middle value when sorted. Best / Worst: max and min. % Positive: share of windows with return > 0.
The series is segmented by calendar year:
return = (endValue ÷ startValue − 1) × 100
startValue is the last value of the prior year (or the first value for the initial year). Partial first/last years are flagged. Dividends, taxes, and transaction costs are scaled proportionally to the initial investment.